Kit for detecting the ApoE4 allele, and for diagnosing the exist

Details Kit for detecting the ApoE4 allele, and for diagnosing the exist Kit for detecting the ApoE4 allele, and for diagnosing the exist

1995-05-15

1998-02-10

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 71, 435810, C12Q 168, G01N 3353

Patent

active

057168288

ABSTRACT:
Methods of diagnosing or prognosing Alzheimer's disease in a subject are disclosed. The methods involve directly or indirectly detecting the presence or absence of an apolipoprotein E type 4 (ApoE4) isoform or DNA encoding ApoE4 in the subject. The presence of ApoE4 indicates the subject is at risk of developing Alzheimer's disease. A novel immunochemical assay for detecting the presence or absence of the Apoliprotein E (ApoE) E4 allele in a subject is also disclosed.

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