Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or... – Including perfusion; composition therefor
Patent
1990-01-23
1992-09-22
Rosen, Sam
Chemistry: molecular biology and microbiology
Differentiated tissue or organ other than blood, per se, or...
Including perfusion; composition therefor
62 64, 623 12, A01N 102
Patent
active
051496216
ABSTRACT:
A device for use in cryopreservation of blood vessels comprising a pair of stylets insertable into the ends of a dissected blood vessel segment. The stylets are mountable on a support track whereby the blood vessel can be distended and supported during cryopreservation procedures. Also disclosed is a freezing and thawing profile capable of maximizing endothelial cell survival. The use of chondroitin sulfate or similar compound is discussed as a novel cryoprotectant and DMSO is disclosed as a penetrating cyroprotectant.
REFERENCES:
patent: 4959319 (1990-09-01), Skelnik et al.
Mueller-Schweinitzer-Chem. Abst. vol. 104 (1986) 145020g.
Bank Harvey L.
Brockbank Kelvin G. M.
Heacox Albert E.
McCaa Cameron
McNally Robert T.
CryoLife, Inc. & Medical Univ. of South Carolina
Rosen Sam
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