Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic
Patent
1995-05-19
1996-11-05
Housel, James C.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is inorganic
435975, 436518, 436524, 436529, G01N 33551, G01N 33553
Patent
active
055717268
ABSTRACT:
A method and test kit useful in a wide variety of immunoassay systems. A method of producing metal sol reagents containing metal sol particles of a preselected size is provided. A metal containing solution is reduced under optimized pH conditions to produce metal sol particles of a preselected size, the particles are coated with a coupling compound and then bound with at least one selected immunochemically reactive component. Particles having different immunochemical specificities are also mixed to produce reagents having multiple selected immunochemical specificities.
REFERENCES:
patent: 4179404 (1979-12-01), Barone
patent: 4313734 (1982-02-01), Leuvering
patent: 4654322 (1987-03-01), Holbein et al.
patent: 4677057 (1987-06-01), Curtiss et al.
patent: 4775636 (1988-10-01), Moeremans et al.
patent: 4920061 (1990-04-01), Poynton et al.
Roth The Colloidal Gold Marker System for Light and Electron Microscopic Cytochemistry Bullock and Petrusz eds. Techniques in Immunocytochemistry 2 217-284.
Horisberger Colloidal Gold: A Cytochemical Marker For Light and Fluorescent Microscopy and For Transmission and Scanning Electron Microscopy SEM 1981 11:9-31.
Weiser The Colloidal Elements Inorganic Colloid Chemistry, J. Wiley & Sons 1933 1-107.
Geoghegon Immunoassays at the Microscopic Level: Solid-Phase Colloidal Gold Methods J. Clin Immunoassay 1988 11(1):11-23.
Frens Controlled Nucleation for the Regulation of the Particle Size in Monodisperse Gold Suspensions Nature Physical Sci. 1973 241:20-22.
Goodman et al. A Review of the Colloidal Gold Marker System SEM 1980 11:133-146.
Janssen manual entitled "Colloidal Gold Sols for Macromolecular Labelling" 1985.
Microparticle Immunoassay Techniques 1988 29-31.
Clark, Experimental Biochemistry 1977 72-73.
Horisberger, et al Colloidal Gold Granules as Markers for Cell Surface Receptors in the Scanning Electron Microscope Specialia 1975 1147-1149.
Leuvering, et al Sol Particle Immunoassy (SPIA) Journal of Immunoassay 1980 1(1) 77-91.
Faulk, et al An immunocolloid method for the electron microscope Immunochemistry 1971 8:1081-1083.
Horisberger, et al Colloidal Gold, A Useful Marker For Transmission and Scanning Electron Microscopy Journal of Histochemistry and Cytichemistry 1977 25:295-305.
Fieser, et al Reagents for Organic Synthesis preface and 411-515.
Cottonb et al Advanced Inorganic Chemistry perface, 752 and 757-758.
Allinger et al., Organic Chemistry, Worth Publishers, Inc. (1971).
Bullock, G. R. & Petrusz, Pr. (eds.) "Techniques in Immuno-cytochemistry 2", pp. 217-284.
Mochnal, et al A Colloidal Gold Immunochromatographic Method Abstract 21st Annual Oak Ridge Conference, Omni at Horton Plaza, San Diego, CA, Apr. 13-14, 1989.
Orchin et al., The Vocabulary of Organic Chemistry, John Wiley & Sons, New York (1980).
Morrison and Boyd, Organic Chemistry, Fourth Edition, New York University, Allyn and Bacon, Inc. (1983).
Brooks, Jr. Houston G.
Chakraborty Utpal R.
Chang Chi-Deu
Graham, Jr. Henry A.
Hollenbeck, Jr. Lloyd L.
Chin Christopher L.
Housel James C.
Ortho Diagnostic Systems Inc.
LandOfFree
Kit containing glutaraldehyde coated colloidal metal particles o does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Kit containing glutaraldehyde coated colloidal metal particles o, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Kit containing glutaraldehyde coated colloidal metal particles o will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2014538