Kit and method for determining a plurality of analytes

Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing

Reexamination Certificate

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C422S050000, C422S051000, C422S051000, C422S082050, C422S082110, C435S006120, C435S007200, C435S287900, C435S288700, C435S808000, C435S975000, C436S164000, C436S172000, C436S518000, C436S524000, C436S525000, C436S805000, C436S808000

Reexamination Certificate

active

10296851

ABSTRACT:
The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprisinga sensor platform comprising an optical thin-film waveguide with a layer (a) transparent at least at an excitation wavelength on a layer (b) with lower refractive index than layer (a), also transparent at least at said excitation wavelength, and at least one grating structure (c) modulated in said layer (a), for the incoupling of said excitation light into layer (a),at least one array of biological or biochemical or synthetic recognition elements immobilized in discrete measurement areas (d) directly or by means of an adhesion-promoting layer on layer (a), for specific recognition and/or binding of said analytes and/or for specific interaction with said analytes,means for laterally resolved referencing of the excitation light intensity available in the measurement areas, and optionallymeans for the calibration of one or more luminescences generated in the near-field of layer (a) as a consequence of the binding of one or more analytes or of the specific interaction with one or more analytes,wherein a liquid sample to be analyzed for said analytes is brought into contact with said measurement areas on said sensor platform either directly or after mixture with further reagents. The invention is also related to analytical systems based on a kit according to the invention and to methods for the determination of one or more analytes, based on said kit, and to use thereof.

REFERENCES:
patent: 5432099 (1995-07-01), Ekins
patent: 5455178 (1995-10-01), Fattinger
patent: 5523089 (1996-06-01), Bergstrom et al.
patent: 5525466 (1996-06-01), Slovacek et al.
patent: 5631170 (1997-05-01), Attridge
patent: 5738992 (1998-04-01), Cook et al.
patent: 5747274 (1998-05-01), Jackowski
patent: 5807755 (1998-09-01), Ekins
patent: 5814565 (1998-09-01), Reichert et al.
patent: 5837551 (1998-11-01), Ekins
patent: 5874219 (1999-02-01), Rava et al.
patent: 5961923 (1999-10-01), Nova et al.
patent: 6485690 (2002-11-01), Pfost et al.
patent: 6653151 (2003-11-01), Anderson et al.
patent: 0 093 613 (1983-11-01), None
patent: 84/01031 (1984-03-01), None
patent: WO 95/03538 (1995-02-01), None
patent: 95/33197 (1995-12-01), None
patent: 95/33198 (1995-12-01), None
patent: 96/35940 (1996-11-01), None
patent: 97/35181 (1997-09-01), None
patent: 98/22799 (1998-05-01), None
patent: 98/29736 (1998-07-01), None
T.E. Plowman et al.: “Multiple-analyte Fluoroimmunoassay Using an Integrated Optical Waveguide Sensor”; Analytical Chemistry, American Chemical Society, Columbus, U.S., vol. 71, No. 19, Oct. 1, 1999, pp. 4344-4352,XP-000854131, ISSN: 0003-2700, whole document.
C. A. Rowe et al.: “Array Biosensor for Simultaneous Identification of Bacterial, Viral, and Protein Analytes”, Analytical Chemistry, American Chemical Society, Columbus, U.S., vol. 71, 1999, pp. 3846-3854, XP-000996992, ISSN: 0003-2700, whole document.
L.G. Mendoza: “High-Throughput Microarray=Based Enzyme-Linked Immunosorbent Assay (ELISA)”, Biotechniques, Eaton Publishing, Natick, U.S., vol. 27, No. 4, Oct. 1999, pp. 778-780, 782-786, 788, XP-000992893, ISSN: 0736-6205, whole document.

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