Kininogen agent promoting bone formation and inhibiting bone res

Details Kininogen agent promoting bone formation and inhibiting bone res Kininogen agent promoting bone formation and inhibiting bone res

1997-01-28

1999-03-23

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 16, A61K 3800

Patent

active

058859640

ABSTRACT:
The present invention will provide an agent promoting bone formation and inhibiting bone resorption comprising kininogen and degradation product of kininogen as an effective ingredient. Fragment 1.multidot.2 is a preferable degradation product of kininogen.
Further, the present invention will provide a drink, food, medicine and feed combined with kininogen and degradation product of kininogen.

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K. Kussendrager, "Lactoferrin and Lactoperoxydase, Bio-Active Milk Proteins" IFI NR.6, pp. 17-21 (1993).
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O. Ljunngren et al., "Stimulation of Bone Resorption in Cultured Mouse Calvaria by Met-Lys-Bradykinin" J. Periodontal Res. 23(1):75-77 (1988)--Abstract.

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