Kinesin polypeptides, polynucleotides encoding same and...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C436S518000

Reexamination Certificate

active

07829296

ABSTRACT:
An isolated polynucleotide comprising a nucleic acid sequence encoding a KIF18A polypeptide being expressed in mesenchymal stem cells is disclosed. Methods of detecting same are disclosed as well as methods of using same for modulating estrogen signaling in cells.

REFERENCES:
patent: WO 02/12268 (2002-02-01), None
patent: WO 2004067779 (2004-08-01), None
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Ngo et al. (1995) “The Protein Folding Problem and Tertiary Structure Prediction, Chapter 14: Computational Complexity Protein Structure Prediction, and the Levinthal Paradox” pp. 433-506 Editor by Merz et al.
Bork (2000) Genome Research 10:398-400; Skolnick (2000) Trends in Biotech. 18: 34-39.
Smith et al. (1997) Nature Biotechnology 1999 15: 1222-1223).
Luboshits et al. “A Unique Human Kinesin-Related Protein Expressed by Marrow Stromal Cells”, Journal of Bone and Mineral Research, 15, (Suppl. 1): S383, 2000. & 22nd Annual Meeting of the American Society for Bone and Mineral Research, Toronto, CA, Sep. 2002.
Luboshits et al. “MS-KIF18A, New Kinesin; Structure and Cellular Expression”, Gene: An International Journal on Genes and Genomes, 351: 19-28, 2005.
Wang et al. “Method for Preparing Male-Sterile Mouse Model”, Database Caplus Chemical Abstracts Service, CN1795929, 2004. Abstract.
International Preliminary Report on Patentability Dated Nov. 8, 2007 From the International Bureau of WIPO Re.: Application No. PCT/IL2006/000506.

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