Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase
Reexamination Certificate
2008-05-07
2010-02-02
Monshipouri, Maryam (Department: 1656)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving transferase
Reexamination Certificate
active
07655432
ABSTRACT:
Novel kinase polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length kinase proteins, the invention further provides isolated kinase fusion proteins, antigenic peptides, and anti-kinase antibodies. The invention also provides kinase nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a kinase gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
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NCBI Entrez Protein Query, GenBank Report for Accession No. AAB71795, Federspiel et al., Direct Submission, Submitted Jun. 5, 1997. Amino Acid Residues 1-645 are SEQ ID Nos. 15 and 16.
NCBI Entrez Protein Query, GenBank Report for Accession No. AAB65490, Rounsley et al., Direct Submissions, Submitted Apr. 4, 1997. Amino Acid Residues 1-604 are SEQ ID No. 17.
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NCBI Entrez Protein Query, GenBank Report for Accession No. P80192, Dorow et al., “Identification of a New Family of Human Epithelial Protein Kinase Containing Two Leucine/Isoleucine-zipper Domains,” Eur. J. Biochem., 1993, pp. 701-710, vol. 213. Amino Acid Residues 1-394 are SEQ ID No. 19.
Database EST, Accession No. AA740847, NCI-CGAP http://www.ncbi.nlm.nih.gov
cicga;, National Cancer Genome Project (CGAP), Tumor Gene Index, Feb. 7, 1998. See their sequence for having at least 15 nucleotides of SEQ ID No. 1 and having the potential of encoding 15 amino acids (fragments) of SEQ ID O:2.
Colman, Research in Immunology, 1994; 145(1):33-36.
Millennium Pharmaceuticals Inc.
Monshipouri Maryam
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