Kinases and uses thereof

Details Kinases and uses thereof Kinases and uses thereof

2008-09-16

2008-09-16

Monshipouri, Maryam (Department: 1656)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving transferase

C435S194000

Reexamination Certificate

active

11358419

ABSTRACT:
Novel kinase polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length kinase proteins, the invention further provides isolated kinase fusion proteins, antigenic peptides, and anti-kinase antibodies. The invention also provides kinase nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a kinase gene has been introduced or disrupted. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.

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Blast N Analysis of SEQ ID No. 1 vs. Nucleotide Patent Database.
Blast X Analysis of SEQ ID No. 2 vs. PNU Database.
Blast X Analysis of SEQ ID No. 2 vs. Protein Patent Database.
Blast N ORF (open reading frame) Analysis of SEQ ID No. 1 vs. Nucleotide dbEST, NUcleotide Patent Preview, and Nucleotide Patent Databases; and Blast X analysis of SEQ ID No. 2 vs. Protein and Protein Patent Database.
Blast N Analysis of SEQ ID No. 3 vs. Nucleotide Patent and Nucleotide Patent Preview Database.
Blast X Analysis of SEQ ID No. 4 vs. PNU and Protein Patent Database.
Blast N Analysis of ORF SEQ ID No. 3 vs. Nucleotide dbEST, Nucleotide Patent Preview, and Nucleotide Patent Databases; and Blast X Analysis of SEQ ID No. 4 vs. Protein and Protein Patent Databases.
Blast N Analysis of ORF of SEQ ID No. 5 vs. Nucleotide dbEST, Nucleotide patent Preview, and Nucleotide Patent Databases; and Blast X Analysis of SEQ ID No. 6 vs. Protein and Protein Patent Databases.
Blast N Analysis of ORF of SEQ ID No. 7 vs. Nucleotide dbEST, Nucleotide Patent Preview, and Nucleotide Patent Databases; and Blast X Analysis of SEQ ID No. 8 vs. Protein and Protein Patent Databases.
Blast N Analysis of ORF of SEQ ID No. 9 vs. Nucleotide dbEST, Nucleotide Patent Preview, and Nucleotide Patent Databases; and Blast X Analysis of SEQ ID No. 10 vs. Protein and Protein Patent Databases.
Blast N Analysis of ORF (partial) of SEQ ID No. 11 vs. Nucleotide, dbEST, Nucleotide Patent Preview, and Nucleotide Patent Databases; and Blast X Analysis of SEQ ID No. 12 vs. Protein and Databases.
Blast N Analysis of ORF of SEQ ID No. 13 vs. Nucleotide dbEST, Nucleotide Patent Preview, and Nucleotide Patent Databases; and Blast X Analysis of SEQ ID No. 14 vs. Protein and Protein Patent Databases.
Database EST, Accession No. AA448898, Hillier et al., WashU-Merck EST Project, Jun. 4, 1997. See the alignment of having at least 15 consecutive nucleotides of SEQ ID No. 1 and having the potential of encoding 15 amino acids of SEQ ID No. 2.
Database EST, Accession No. AA740847, NCI-CGAP http://www.ncbi.nlm.nih.gov
cicga;, National Cancer Genome Project (CGAP), Tumor Gene Index, Feb. 7, 1998. See their sequence for having at least 15 nucleotides of SEQ ID No. 1 and having the potential of encoding 15 amino acids (fragments) of SEQ ID O:2.
Colman, Research in Immunology, 1994; 145(1):33-36; (Cited by examiner in PTO-892 form in U.S. Appl. No. 10/989,228).
NCBI Entrez Protein Query, GenBank Report for Accession No. AAB71795, Federspiel et al., Direct Submission, Submitted Jun. 5, 1997. Amino Acid Residues 1-645 are SEQ ID Nos. 15 and 16.
NCBI Entrez Protein Query, GenBank Report for Accession No. AAB65490, Rounsley et al., Direct Submissions, Submitted Apr. 4, 1997. Amino Acid Residues 1-604 are SEQ ID No. 17.
NCBI Entrez Protein Query, GenBank Report for Accession No. AAC47047, Wilson et al., “2.2 Mb of Contiguous Nucleotide Sequence from Chromosome III of C. elegans,” Nature, 1994 pp. 32-38, vol. 368; Waterston, Direct Submission, Submitted Apr. 8, 1994. Amino Acid Residues 1-328 are SEQ ID Nos. 18.
NCBI Entrez Protein Query, GenBank Report for Accession No. P80192, Dorow et al., “Identification of a New Family of Human Epithelial Protein Kinase Containing Two Leucine/Isoleucine-zipper Domains,” Eur. J. Biochem., 1993, pp. 701-710, vol. 213. Amino Acid Residues 1-394 are SEQ ID No. 19.
Database EST, Accession No. AA448898, Hillier et al., WashU-Merck EST Project, Jun. 4, 1997. See the alignment of having at least 15 consecutive nucleotides of SEQ ID No. 1 and having the potential of encoding 15 amino acids of SEQ ID No. 2.
Database EST, Accession No. AA740847, NCI-CGAP http://www.ncbi.nlm.nih.gov
cicga;, National Cancer Genome Project (CGAP), Tumor Gene Index, Feb. 7, 1998. See their sequence for having at least 15 nucleotides of SEQ ID No. 1 and having the potential of encoding 15 amino acids (fragments) of SEQ ID O:2.

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