Perfume compositions – Perfume compositions – With preservative – stabilizer – or fixative
Reexamination Certificate
2005-03-08
2005-03-08
Helms, Larry R. (Department: 1642)
Perfume compositions
Perfume compositions
With preservative, stabilizer, or fixative
C435S375000
Reexamination Certificate
active
06864224
ABSTRACT:
The invention relates to the discovery of a novel amino acid sequence motif, herein termed the RKIP motif, and to the family of proteins defined by the presence of that motif. Proteins comprising the RKIP motif modulate kinases involved in signal transduction pathways. The RKIP motif forms the basis for screening assays for the identification of agents useful for modulating signal transduction pathways subject to RKIP family mediated regulation, and for the diagnosis and treatment of disorders involving inappropriate activities of pathways subject to RKIP family medicated regulation.
REFERENCES:
patent: 4925677 (1990-05-01), Feijen
patent: 6187799 (2001-02-01), Wood et al.
Jelinek et al (Mar. 1996, Molecular and Cellular Biology, vol. 16, pp. 1027-1034).*
Berg et al (Mar. 5, 1999, Cancer Research 59, 1180-1183).*
Kastin, AJ, 2001, Life Science, 69(11): 1305-12.*
Frost, SJ, 1993, J Cell Biochem, 52(2): 227-36.*
Selbo et al (2002, Tumour Biol 23, 103-12, abstract only).*
Yeung et al (May 2000, Molecular and Cellular Biology, vol. 21, pp. 7207-7217).*
Yeung et al (1999, Nature, vol. 401, pp. 173-177).*
Ferrell, Jr., MAP Kinases in Mitogenesis and Development, 1996,Current Topics in Developmental Biology, 33: 1-60.
Morrison, et al., The complexity of Raf-1 regulation, 1997,Cell Biol.,9: 174-179.
Moddie, et al., Complexes of Ras-GTP with Raf-1 and Mitogen-Activated Protein Kinase Kinase, 1993,Science, 260: 1658-1661.
Schaeffer, et al, MPI: A MEK Binding Partner that Enhances Enzymatic Activation of the MAP Kinase Cascade, 1998,Science, 281:1668-1671.
Kolch Walter
Sedivy John M.
Yeung Kam Chi
Brown University Research Foundation
Helms Larry R.
Palmer & Dodge LLP
Spar Elizabeth
Williams Kathleen M.
LandOfFree
Kinase inhibitors and methods of use in screening assays and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Kinase inhibitors and methods of use in screening assays and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Kinase inhibitors and methods of use in screening assays and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3390703