Kinase inhibitor scaffolds and methods for their preparation

Details Kinase inhibitor scaffolds and methods for their preparation Kinase inhibitor scaffolds and methods for their preparation

2007-02-13

2007-02-13

Berch, Mark L. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C544S264000, C544S276000, C544S265000, C544S224000, C544S237000, C544S239000, C544S336000, C544S408000, C544S316000, C544S320000, C544S322000, C544S323000, C544S326000, C544S330000, C544S286000, C544S287000, C544S291000, C544S292000, C544S293000, C544S353000, C544S354000, C546S304000, C546S307000, C546S312000, C546S153000, C546S159000, C546S160000, C546S171000, C435S004000, C548S557000, C548S558000, C548S559000, C548S469000, C548S483000, C548S484000, C548S306400, C548S307400, C548S307700, C548S308100

Reexamination Certificate

active

10270030

ABSTRACT:
General methods for the solution phase as well as solid phase synthesis of various substituted heteroaryls has been demonstrated. These substituted heteroaryls can be further elaborated by aromatic substitution with amines at elevated temperature or by anilines, boronic acids and phenols via palladium catalyzed cross-coupling reactions.

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