Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Urogenital system
Patent
1996-06-27
1997-12-09
Witz, Jean C.
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
Urogenital system
A61K 3523
Patent
active
056957858
ABSTRACT:
The invention is directed to a method of treating systematic lupus erythematosus (SLE) in animals, including humans, by the oral administration of kidney extracts to decrease anti-DNA antibody production. The method of the invention includes both prophylactic and therapeutic measures.
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Yves Borel et al., "Prevention of Murine Lupus Nephritis by Carrier-Dependent Induction of Immunologic Tolerance to Denatured DNA", Science, 182:76-78.
Lewis P. Parker et al., "Modification of NZB/NZWF.sub.1 Autoimmune Disease by Development of Tolerance to DN", The Journal of Immunology, 113:292-297.
Yves Borel et al., "Treatment of Lupus Nephritis in Adult (NZB+NZW)F.sub.1 Mice by Cortisone-Facilitated Tolerance to Nucleic Acid Antigens", The Journal of Clinical Investigation, 61:276-286.
Masonic Medical Research Laboratory
Witz Jean C.
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