Kidney disease targets and uses thereof

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C424S130100, C424S178100

Reexamination Certificate

active

07608413

ABSTRACT:
The present invention provides a method for diagnosing and detecting diseases associated with kidney. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in kidney diseases (KCAT) and antibodies binds to KCATs. The present invention provides that KCATs are used as targets for screening agents that modulates the KCAT activities. Further the present invention provides methods for treating diseases associated with kidney.

REFERENCES:
patent: WO 0055318 (2000-09-01), None
patent: WO 0250114 (2002-06-01), None
Lomri, Fitz, and Scharschmidt. Hepatocellular transport: role of ATP-binding cassete proteins. Seminars in Liver Disease, 1996. vol. 16, pp. 201-210.

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