Ketone derivatives and their medical applications

Details Ketone derivatives and their medical applications Ketone derivatives and their medical applications

1999-05-25

2000-08-08

Lambkin, Deborah C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514457, 514460, 514432, 514444, 549 59, 549 54, 549 55, 549 28, 549 23, 549289, 549287, 549291, 549305, 549313, 549318, A61K 3138, A61K 3135, C07D40900, C07D33364, C07D31104

Patent

active

061002925

ABSTRACT:
This invention relates to ketones represented by the following formula ##STR1## and to drugs in which such a ketone or pharmacologically acceptable salt thereof is an effective component.
The ketones of the present invention encourage the production of platelets, red blood cells, white blood cells and the like, and can be used to prevent or treat cytopaenia brought about by cancer chemotherapy, radiotherapy, bone marrow transplantation and drug therapy, or by immunological abnormality or anaemia, and the like.

REFERENCES:
patent: 3963756 (1976-06-01), Ohno et al.
patent: 4061769 (1977-12-01), Ohno et al.
patent: 5059620 (1991-10-01), Stout et al.
patent: 5073563 (1991-12-01), Frickel et al.
patent: 5424320 (1995-06-01), Fortin et al.
patent: 5905088 (1999-05-01), Diaz et al.
J. Med. Chem. 1993, 36, 3386-3396 Rowley et al 3-Acyl-4-hydroxyquinolin-2(1H)-ones.

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