Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Glucose – ketone – nitrate standard or control
Patent
1982-12-06
1985-05-14
Gron, Teddy S.
Chemistry: analytical and immunological testing
Composition for standardization, calibration, simulation,...
Glucose, ketone, nitrate standard or control
436128, 436169, 422 56, G01N 3348
Patent
active
045173010
ABSTRACT:
A composition, device and method for preparing a ketone control solution are disclosed. The composition comprises dimethylformamide and a Group I, II or III metal salt of a .beta.-keto acid ester. The salt has the structure ##STR1## in which R is lower alkyl of 1 to 6 carbon atoms, R' is an aliphatic or cyclic group having 1 to about 7 carbon atoms, M is a Group I, II or III metal ion and n is 1, 2 or 3. A carrier matrix incorporated with the composition can be affixed to a support member to form the device. Preferably, a hydrolyzing agent is included on the device in the same or another carrier matrix. The method for preparing the control solution comprises contacting a predetermined volume of an aqueous solution with the device for a predetermined time.
REFERENCES:
patent: 2509140 (1950-05-01), Free
patent: 4071317 (1978-01-01), Lam
patent: 4193766 (1980-03-01), Daunora et al.
patent: 4298498 (1981-11-01), Rehner et al.
patent: 4372747 (1983-02-01), Gabbay et al.
Coe Roger N.
Gron Teddy S.
Kilby Catherine S.
Miles Laboratories Inc.
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