Ketolides from the class of 15-membered lactams

Details Ketolides from the class of 15-membered lactams Ketolides from the class of 15-membered lactams

1998-07-31

2000-08-29

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

540454, A61K 3135, C07D26700, A61P 3104

Patent

active

061109657

ABSTRACT:
The present invention relates to the new 15-membered ketoazalides from the class of 6-O-methyl-8a-aza-8a-homo-and 6-O-methyl-9a-aza-9a-homoerythromycin A with the general formula (I) ##STR1## wherein A represents NH group and B at the same time represents C.dbd.O group, or

REFERENCES:
patent: 5202434 (1993-04-01), Wilkening
Waddell et al., Synthesis and Antibacterial Activity of O-methyl Derivatives of Azalide Antibiotics, Bioorganic & Medicinal Chemisty Letters, vol. 8, No. 11, pp. 1321-1326, Jun. 1998.

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