Compositions – Compositions containing a single chemical reactant or plural... – Organic reactant
Patent
1994-04-07
1995-10-10
Lieberman, Paul
Compositions
Compositions containing a single chemical reactant or plural...
Organic reactant
252173, 25217411, 25217423, 252544, 252547, 252551, 252555, 252399, 252DIG13, 514852, 514881, C11D 348
Patent
active
054568510
ABSTRACT:
A shampoo that contains ketoconazole, a surfactant, a foaming agent, thickener sufficient to give the final formulation a viscosity in the range of about 4,000 to about 9,000 cps at room temperature (i.e., about 20.degree.-25.degree. C.), preservative, butylated hydroxytoluene or butylated hydroxyanisole in an amount sufficient to retard degradation of the ketoconazole, and acid, base or buffer sufficient to give the final composition a pH in the range of from about 4 to about 10.
REFERENCES:
patent: 4608392 (1986-08-01), Jacquet et al.
patent: 5061700 (1991-10-01), Dow et al.
patent: 5310545 (1994-05-01), Eisen
Berger et al., "Double-Blind Placebo-Controlled Trial of Ketoconazole 2% Shampoo in the Treatment of Moderat to Severe Dandruff", Adv. Ther., 7(5), Sep./Oct. 1990, pp. 247-256.
Go et al., "A Double-Blind Trial of 1% Ketoconazole Shampoo Versus Placebo in the Treatment of Dandruff", Mycoses, 35(3-4), 1992, pp. 103-105.
Danby et al., "A Randomized Double-Blind, Placebo-Controlled Trial of Ketoconazole 2% Shampoo Versus Selenium Sulfide 2.5% Shampoo . . . ", Journal of the American Academy of Dermatology, 29(6), Dec. 1993, pp. 1008-1012.
Liu Jue-Chen
Wang Jonas C. T.
Yusuf Mohammed
Douyon Lorna M.
Johnson & Johnson Consumer Products, Inc.
Lieberman Paul
Metz Charles J.
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