Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1991-07-18
1993-10-05
Dees, Jose J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
5483041, 558262, 560 27, 564192, 564194, 564307, 564219, 568329, C07C23306, C07C23718
Patent
active
052507327
ABSTRACT:
5,6-Dehydronorketamine and derivatives retaining the .alpha.,.beta.-unsaturated carbonyl are disclosed. These and other Michael or Michael-type acceptors and adducts are shown to influence the replication, differentiation or maturation of blood cells, especially platelet progenitor cells. Accordingly, these compounds are used for treatment of thrombocytopenia.
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Kogan Timothy P.
Somers Todd C.
Dees Jose J.
Frazier B.
Genentech Inc.
Winter Daryl B.
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