Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugate includes potentiator; or composition comprising...
Patent
1982-11-05
1984-03-13
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugate includes potentiator; or composition comprising...
536 61, A61K 31585, C07J 1900
Patent
active
044367350
ABSTRACT:
The present invention provides ketals of 3'"-dehydrocardenolide tridigitoxosides of the general formula: ##STR1## in which R.sub.1 and R.sub.2 are identical alkyl radicals containing up to 3 carbon atoms or together represent a cyclic ketal containing 2 to 6 carbon atoms, R.sub.3 represents two hydrogen atoms, the group ##STR2## or the radical ##STR3## wherein R.sub.1 and R.sub.2 have the above-given meaning, and R.sub.4 is a hydrogen atom or a lower acyl or alkyl radical.
The present invention also provides processes for the preparation of these ketals, as well as pharmaceutical compositions containing them, which are useful for the treatment of cardiac insufficiency.
REFERENCES:
patent: 3907775 (1975-09-01), Losel et al.
patent: 3909357 (1975-09-01), Reinhard et al.
Hoyer Edgar
Kaiser Fritz
Neubert Peter
Schaumann Wolfgang
Voigtlander Wolfgang
Boehringer Mannheim GmbH
Brown Johnnie R.
Peselev Elli
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