Keratinocytes expressing exogenous angiogenic growth factors

Details Keratinocytes expressing exogenous angiogenic growth factors Keratinocytes expressing exogenous angiogenic growth factors

2011-03-29

2011-03-29

Zara, Jane (Department: 1635)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Primate cell, per se

C424S093210, C424S422000, C424S423000, C435S242000, C435S395000, C435S455000, C514S04400A, C536S023100, C536S023500

Reexamination Certificate

active

07915042

ABSTRACT:
The present invention relates to in vitro cultured skin tissue, and in particular to cultured skin tissue comprising exogenous genes encoding angiogenic growth factors. In some embodiments, the keratinocytes express exogenous angiopoietin-1 or a member of the VEGF family, preferably VEGF-A. In particularly preferred embodiments, the keratinocytes are incorporated into cultured skin tissue.

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