Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-02-13
2000-06-20
Ulm, John
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435325, 435243, 4353201, 514 2, 514 12, 514925, 530300, 530324, 530328, 530399, 530402, 536 2351, A61K 3818, C07K 1450, C12N 1518, C12N 1563
Patent
active
060776927
ABSTRACT:
This invention relates to newly identified polynucleotides, polypeptides encoded by such polynucleotides, the use of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides. More particularly, the polypeptide of the present invention is a Keratinocyte Growth Factor, sometimes hereinafter referred to as "KGF-2" also formerly known as Fibroblast Growth Factor 12 (FGF-12). This invention further relates to the therapeutic use of KGF-2 to promote or accelerate wound healing. This invention also relates to novel mutant forms of KGF-2 that show enhanced activity, increased stability, higher yield or better solubility.
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English language translation/equivalent of WO 97/20929 (AM3).
Coleman Timothy A.
Dillon Patrick J.
Duan D. Roxanne
Gentz Reiner L.
Gruber Joachim R.
Human Genome Sciences Inc.
Saoud Christine
Ulm John
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