Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1995-05-30
2000-05-02
Hauda, Karen M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
4353201, 435371, 435375, A61K 4800, C12N 510, C12N 1509
Patent
active
060572981
ABSTRACT:
A keratin K1 vector for expression of a nucleic acid sequence in an epidermal cell. The vector includes a 5' flanking region which includes necessary sequences for expression of a nucleic acid cassette, a keratin K1 3' flanking region which regulates expression of a nucleic acid sequence, predominantly in the epidermis, and a linker which connects the 5' flanking region to a nucleic acid. The linker has a position for inserting a nucleic acid cassette. The linker does not contain the coding sequence of a gene that the linker is naturally associated with. That is, the linker is not the normal gene associated with the 5' and 3' regions.
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Greenhalgh David A.
Roop Dennis R.
Rothnagel Joseph A.
Yuspa Stuart H.
Baylor College of Medicine
Hauda Karen M.
The United States of America as represented by the Department of
LandOfFree
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