Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1998-11-13
2000-05-16
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
435212, 435219, C12P 2100, C12N 948, C12N 950
Patent
active
060635924
ABSTRACT:
A method for cleaving polypeptides includes contacting a polypeptide with a recombinant or isolated Kell protein having proteolytic activity for the polypeptide. A method for converting big endothelins-1, -2 and -3 to endothelins-1, -2 and -3 respectively comprises contacting the big endothelin with Kell protein having proteolytic activity for cleaving big endothelin-1, -2 and -3 to endothelin-1, -2 or -3 respectively. In another embodiment, the Kell protein cleaves vasoactive intestinal peptide.
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New York Blood Center Inc.
Wax Robert A.
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