Kappa opioid receptor ligands

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S241000, C514S256000, C514S291000, C514S292000, C514S293000, C514S307000, C514S311000, C544S180000, C544S333000, C546S081000, C546S082000, C546S084000, C546S139000, C546S152000, C540S577000

Reexamination Certificate

active

06974824

ABSTRACT:
Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors relative to nor-BNI, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor such as heroin or cocaine addictions.

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patent: 6159990 (2000-12-01), Lagu et al.
patent: 6218390 (2001-04-01), Lagu et al.
patent: 6268369 (2001-07-01), Nagarathnam et al.
patent: 2002/0013321 (2002-01-01), Liras
patent: 2004/0072865 (2004-04-01), Bouillot et al.
patent: 1 038 872 (2000-09-01), None

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