Kappa agonist compounds pharmaceutical formulations and method o

Details Kappa agonist compounds pharmaceutical formulations and method o Kappa agonist compounds pharmaceutical formulations and method o

1997-07-14

1998-06-09

McKane, Joseph

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514 85, A61K 31495

Patent

active

057634459

ABSTRACT:
Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided.
The compounds of formular I, II, III and IV have the structure: ##STR1## wherein X, X.sub.4, X.sub.5, X.sub.7, X.sub.9 ;

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