Kappa agonist compounds pharmaceutical formulations and method o

Details Kappa agonist compounds pharmaceutical formulations and method o Kappa agonist compounds pharmaceutical formulations and method o

1998-10-30

2000-05-02

McKane, Joseph K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514 85, 544337, 544358, 544359, 544360, 544372, 544383, 544386, 544387, 544389, A61K 31495, C07D24104

Patent

active

060573236

ABSTRACT:
Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics and anti-pruritic agents are provided.
The compound of formula I, having the structure: ##STR1## wherein R.sub.1, R.sub.2 ;

REFERENCES:
patent: 4065573 (1977-12-01), Lednicer
patent: 4098904 (1978-07-01), Szmuszkovicz
patent: 4145435 (1979-03-01), Szmuszkovicz
patent: 4212878 (1980-07-01), Lednicer et al.
patent: 4359476 (1982-11-01), Kaplan et al.
patent: 4438130 (1984-03-01), Kaplan
patent: 4663343 (1987-05-01), Horwell et al.
patent: 4855316 (1989-08-01), Horwell et al.
patent: 4906655 (1990-03-01), Horwell et al.
patent: 5646151 (1997-07-01), Kruse et al.
patent: 5688955 (1997-11-01), Kruse et al.
patent: 5744458 (1998-04-01), Kruse et al.
McMahon et al., TINS, vol. 15, No. 12 (1992).
Bernstein et al., Journal of Investigative Dermatology, 78: 82-83 (1982).
Ballantyne et al., Pain, 33: 149-160 (1988).
J. D. Bernhard, J. Am. Acad. Derm. 24: 309 (1991).
IASP Newsletter, Sep./Oct. 1996.
Thomas et al., Brain Research, 695:267-270 (1995).

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