Kappa agonist compounds and pharmaceutical formulations thereof

Details Kappa agonist compounds and pharmaceutical formulations thereof Kappa agonist compounds and pharmaceutical formulations thereof

1997-02-05

1997-11-18

McKane, Joseph

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548413, 548465, 548517, 548527, 548556, 548568, 544106, 544111, 544168, 564182, C07D40110

Patent

active

056889550

ABSTRACT:
Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics are provided.
The compounds of formulae I, II, III and IV have the structure: ##STR1## wherein X, X.sub.4, X.sub.5, X.sub.7, X.sub.9 ;

REFERENCES:
patent: 4065573 (1977-12-01), Lednicer
patent: 4098904 (1978-07-01), Szmuszkovicz
patent: 4145435 (1979-03-01), Szmuszkovicz
patent: 4212878 (1980-07-01), Lednicer et al.
patent: 4359476 (1982-11-01), Kaplan et al.
patent: 4438130 (1984-03-01), Kaplan
patent: 4663343 (1987-05-01), Howell et al.
patent: 4855316 (1989-08-01), Horwell et al.
patent: 4906655 (1990-03-01), Horwell et al.
Raynor et al., Molecular Pharmacol., 45: 330-334 (1994).
Wheeler-Aceto et al., Psychopharmacology, 104: 35-44 (1991).

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