Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1996-07-25
1998-12-29
Stucker, Jeffrey
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 234, 536 243, 536 2433, 536 245, 530350, 5303883, 4241591, 4241471, 4241921, 4242291, 435 6, 435 691, 435 693, 4352351, 435325, 4352521, 4353201, A61K 39245, C07H 2104, C07K 1403, C12N 1538
Patent
active
058544186
ABSTRACT:
This invention provides an isolated DNA molecule which encodes viral macrophage inflammatory protein-1.alpha. II (vMIP-1.alpha. II). Antisense and oligonucleotide molecules are also provided.
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Bates (1996) Chemokine receptors and HIV-1: an attractive pair?, Cell 86, 1-3 (Exhibit 3).
Choe et al. (1996) The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates, Cell 85, 1135-1148 (Exhibit 4).
Cocchi et al. (1995) Identification of RANTES, MIP-1-alpha, and MIP-1-beta as the major HIV-suppressive factors produced by CD8+ T cells, Science 270, 1811-1815 (Exhibit 5).
Doranz et al. (1996) A dual-tropic primary HIV-1 isolate that uses uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors, Cell 85, 1149-1158 (Exhibit 6).
Murphy (1994) The molecular biology of leukocyte chemoattractant receptors, Annu. Rev. Immunol. 12, 593-633 (Exhibit 7).
Oppenheim et al. (1991) Properties of the novel proinflammatory supergene "intercrine" cytokine family, Ann. Rev. Immunol. 9, 617-648 (Exhibit 8).
Weiss (1996) HIVreceptors and the pathogenesis of AIDS, Science 272, 1885-1886 (Exhibit 9).
Bohenzky Roy A.
Chang Yuan
Edelman Isidore S.
Moore Patrick S.
Russo James J.
Bui Phuong T.
Stucker Jeffrey
The Trustees of Columbia University in the City of New York
White John P.
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