Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1996-07-25
1999-01-26
Stucker, Jeffrey
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
435 6, 435 691, 435 693, 435 912, 435 914, 4353201, 4352521, 435325, 435243, 536 2372, 530350, 530395, 514 44, C07H 2104, C12N 121, C12N 1538, C12P 1934
Patent
active
058637877
ABSTRACT:
This invention provides an isolated DNA molecule which encodes glycoprotein B (gB). Antisense and triplex oligonucleotide molecules are also provided.
REFERENCES:
Chang et al (1994) Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma, Science 265, 1865-1869 (Exhibit 2).
Farrell et al (1994) Vaccine potential of a herpes simplex virus type 1 mutant with an essential glycoprotein deleted, J Virol 68, 927-932 (Exhibit 3).
Liu et al (1993) Human herpesvirus-6 glycoprotein H and L homologs are components of the gp100 complex and the gH external domain is the target for neutralizing monoclonal antibodies, Virology 197, 12-22 (Exhibit 4).
Moore et al (Jan. 1996) Primary characterization of a herpesvirus agent associated with Kaposi's sarcoma, J Virol 70, 549-558 (Exhibit 5).
Plotkin et al (1990) Vaccines for the prevention of human cytomegalo-virus infection, Rev Infect Dis 12(S), 827-838 (Exhibit 6).
Pulford et al (1994) Expression of the Epstein-Barr virus envelope fusion glycoprotein gp85 gene by a recombinant baculovirus, J Gen Virol 75, 3241-3248 (Exhibit 7).
Roop et al (1993) A mutant herpes simplex virus type 1 unable to express glycoprotein L cannot enter cells, and its particles lack glycoprotein H. J Virol 67, 2285-2297 (Exhibit 8).
Spaete (1991) A recombinant subunit vaccine approach to HCMV vaccine development, Transplant Proc 23, 90-96 (Exhibit 9).
Bohenzky Roy A.
Chang Yuan
Edelman Isidore S.
Moore Patrick S.
Russo James J.
Bui Phuong T.
Stucker Jeffrey
The Trustees of Columbia University in the City of New York
White John P.
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