Kanamycin C derivatives

Details Kanamycin C derivatives Kanamycin C derivatives

1977-09-19

1979-02-20

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 17, C07H 1522

Patent

active

041408497

ABSTRACT:
1-N-(L-4-amino-2-hydroxybutyryl) derivatives of kanamycin C, 3'-deoxykanamycin C and 3',4'-dideoxykanamycin C have been prepared which possess high antibacterial activity against a wide variety of drug-resistant bacteria. These new derivatives are prepared by reacting L-4-amino-2-hydroxybutyric acid or a functional equivalent thereof with the 1-amino group of kanamycin C, 3'-deoxykanamycin C or 3',4'-dideoxykanamycin C.

REFERENCES:
patent: 3781268 (1973-12-01), Kawaguchi et al.
patent: 3939143 (1976-02-01), Umezawa et al.
patent: 4001208 (1977-01-01), Umezawa et al.
patent: 4029882 (1977-06-01), Wright
Fugisawa et al. "The Jour. Of Antibiotics", vol. XXVII, No. 9, 1974, pp. 677-681.

Affiliated with

Also associated with

Rating

Kanamycin C derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Kanamycin C derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Kanamycin C derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-259142