Kallikrein inhibitors and anti-thrombolytic agents and uses...

Details Kallikrein inhibitors and anti-thrombolytic agents and uses... Kallikrein inhibitors and anti-thrombolytic agents and uses...

2007-06-26

2007-06-26

Carlson, Karen Cochrane (Department: 1656)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S324000, C604S004010

Reexamination Certificate

active

11125639

ABSTRACT:
Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an anti-fibrinolytic agent, for preventing or reducing blood loss and/or ischemia, e.g., ischemia associated with perioperative blood loss and cerebral ischemia, the onset of systemic inflammatory response, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia or a focal brain ischemia, e.g., in patients subjected to invasive surgical procedures, especially procedures requiring cardiopulmonary bypass.

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