K04-0144 substance and a process for production thereof

Details K04-0144 substance and a process for production thereof K04-0144 substance and a process for production thereof

2011-07-05

2011-07-05

Ramirez, Delia M (Department: 1652)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S014000, C562S501000

Reexamination Certificate

active

07973147

ABSTRACT:
A microorganism represented by a strain K04-0144 belonging toStreptomycessp. having ability to produce K04-0144 substance is cultured in the medium, and the isolated K04-0144A substance, K04-0144B substance and K04-0144C substance therefrom have strong antibacterial activities against Gram-positive bacteria including methicillin-resistantStreptococcus aureus(MRSA), consequently these are useful as the therapeutic agents for infectious disease caused by MRSA as well as infectious diseases caused by multidrug including β-lactam antibiotics resistant bacteria. Further, similarly, since the novel K04-0144D substance isolated from the cultured liquid has the action for enhancing the effect of β-lactam antibiotics, which are utilized as the antibacterial agents, in combination with them, it is useful as the therapeutic agent for infectious diseases caused by methicillin-resistantStaphylococcus aureus(MRSA) and multidrug including β-lactam antibiotics resistant bacteria.

REFERENCES:
patent: 9-509677 (1997-09-01), None
Donnerstag et al., “A structurally and biogenetically interesting moenomycin antibiotic,” Tetrahedron, vol. 51, No. 7, 1995, pp. 1931-1940.
Hasegawa, “MRSA,” pp. 264-273.

Affiliated with

Also associated with

Rating

K04-0144 substance and a process for production thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with K04-0144 substance and a process for production thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and K04-0144 substance and a process for production thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2621990