Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1988-11-01
1992-03-24
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 946, 435 691, 435948, A01N 6300
Patent
active
050987062
ABSTRACT:
A method of controlling insects comprises administering juvenile hormone esterase during a larval stadium to disrupt normal development. The juvenile hormone esterase is preferably administered by infecting insects with a baculovirus including the gene for juvenile hormone esterase. The enzyme fatally disrupts the normal development of the host insects.
REFERENCES:
patent: 4745051 (1988-05-01), Smith et al.
patent: 4762547 (1988-08-01), Jwosaki et al.
Chem. Abstracts vol. 102, Entry 76006b.
Abdel-Aal et al., "Transition State Analogs as Ligands for Affinity Purification of Juvenile Hormone Esterase", Science, vol. 233, pp. 1073-1076, 1986.
Cheung et al., "Micro-Lipid Droplet Encapsulation of Bacillus thuringiensis subsp. Israelensis, .delta.-Endotoxin for Control of Mosquito Larvae", Appl. Environ. Microbiol., vol. 50, No. 4, pp. 984-988, Oct. 1985.
Hammock et al., "Strategies for the Discovery of Insect Control Agents", Chapter 12 in Steffens et al. (Eds.), Biomechanisms Regulating Growth and Development, USDA Beltsville Symposia vol. 12, Kluwer Academic Press, 1988.
Hammock et al., "Analysis of Juvenile Hormone Esterase Activity", Chapter 32, pp. 487-495, in Law et al. (Eds.), Methods in Enzymology, vol. III: Steroids and Isoprenoids (Part B), Academic Press, 1985.
Hammock et al., "Selective Inhibition of JH Esterases from Cockroach Hemolymph", Pesticide Biochemistry and Physiology, vol. 7, pp. 517-530, 1977.
Hammock Bruce D.
Philpott Matthew L.
Kulkosky Peter F.
Page Thurman K.
The Regents of the University of California
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