Junction-fragment DNA probes and probe clusters

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 5, 435 6, 4351723, 435253, 935 10, 935 23, 935 26, 935 27, 935 31, 935 76, 935 78, 935 80, 935 81, 935 82, 436501, 436504, 436811, 536 27, C12Q 168, C12N 1500

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047104651

ABSTRACT:
A junction-fragment DNA probe, a DNA probe cluster, and methods of preparing and using the probe and cluster to study gene localization and organization. The probe includes first and second gene segments which are derived from first and second, single-copy genomic-DNA gene regions, respectively, separated from one another, in the genomic DNA strand, by a selected distance of between about 20 and 2,000 kilobases. The two segments in the probe are connected at a j

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