Jomol derivatives as agents for the use in malignant tumors and

Details Jomol derivatives as agents for the use in malignant tumors and Jomol derivatives as agents for the use in malignant tumors and

1990-01-22

1992-05-26

Maples, John S.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 11, 4352532, 514 2, 530402, 530403, A61K 3902, C12N 120

Patent

active

051166143

ABSTRACT:
The invention relates to Jomol, processes for its production of Nocardia opaca cells (DSM 43202 or ATCC 21953, respectively), its derivatives, diagnostic compositions, and pharmaceutical preparations containing Jomol or its derivatives, as well as to products containing Jomol and/or one of its derivatives and an adjuvant.

REFERENCES:
patent: 4590060 (1986-05-01), Ehrenfeld
J. Drews (1984): "Immunostimulation, Clinical and Experimental Perspectives" in Klin. Wochenschr. (1984) 62, 254-264.
R. Barot-Ciobaru et al. (1981): "Antitumor activity of intralesionally administered Nocardia opaca preparations in rat and mouse tumors: A comparison with BCG and Corynebacterium parvum" Int. J. Immunopharmac. vol. 3, pp. 115-122 (1981).
C. H. J. Ford and A. G. Casson (1986): Antibody mediated targeting in the treatment and diagnosis of cancer: an overview Cancer Chemother. Pharmacol (1986) 17; 197-208.
G. Poste et al. (1982): "Analysis of the fate of systemically administered liposomes and implications for their use in drug delivery". Cancer Research 42, 1412-1422 (1982).

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