JNK inhibitor

Details JNK inhibitor JNK inhibitor

2007-04-03

2007-04-03

Powers, Fiona T. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S275000, C514S340000, C514S342000, C544S331000, C544S333000, C546S270400, C546S271400

Reexamination Certificate

active

10470751

ABSTRACT:
The present invention relates to a c-Jun N-terminal kinase inhibitor containing an azole compound (I) substituted by a nitrogen-containing aromatic group having substituent(s)(except a compound represented by the formula:) or a salt thereof or a prodrug thereof.

REFERENCES:
patent: 4612321 (1986-09-01), Terao et al.
patent: 5658903 (1997-08-01), Adams et al.
patent: 5792778 (1998-08-01), de Laszlo et al.
patent: 6083949 (2000-07-01), Liverton et al.
patent: 6436966 (2002-08-01), Ohkawa et al.
patent: 6962933 (2005-11-01), Ohkawa et al.
patent: 2002/0032183 (2002-03-01), LoGrasso et al.
patent: 2004/0053973 (2004-03-01), Ohkawa et al.
patent: 0 149 884 (1984-07-01), None
patent: 1070711 (2001-01-01), None
patent: 1180518 (2002-02-01), None
patent: 2000-302680 (2000-10-01), None
patent: WO 97/05877 (1997-02-01), None
patent: WO 97/35856 (1997-10-01), None
patent: WO 97/47618 (1997-12-01), None
patent: WO 98/52940 (1998-11-01), None
patent: WO 98/56788 (1998-12-01), None
patent: WO 99/18942 (1999-04-01), None
patent: WO 99/21555 (1999-05-01), None
patent: WO 99/32121 (1999-07-01), None
patent: WO 99/64418 (1999-12-01), None
patent: WO-00/26209 (2000-05-01), None
patent: WO 00/31063 (2000-06-01), None
patent: WO 00/63204 (2000-10-01), None
patent: WO 00/64894 (2000-11-01), None
patent: WO 01/10865 (2001-02-01), None
patent: WO 01/12621 (2001-02-01), None
patent: WO 01/30778 (2001-05-01), None
patent: WO 01/57022 (2001-08-01), None
patent: WO 01/74811 (2001-10-01), None
patent: WO 02/10137 (2002-02-01), None
Lisnock et al., Biochemistry, 37, 16573-16581, 1998.
Bagowski et al., Current Biology, 11, 1176-1182, 2001.
Davis, Cell, 103, 239-252, Oct. 13, 2000.
Omura et al., J. Mol. Cell Cardiol., 31, 1269-1279, 1999.
Yue et al., Circulation Research, 82, 166-174, 1998.
Liverton, et al. “Design and Synthesis of Potent, Selective, and Orally Bioavailable Tetrasubstituted Imidazole Inhibitors of p38 Mitogen-Activated Protein Kinase” J. Med. Chem. 42:2180-2190 (1999).

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