JM216 formulations

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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Details

424422, 424436, 424486, 424488, 424499, 514492, A61F 1300

Patent

active

061363367

ABSTRACT:
Novel suppository pharmaceutical formulations of the platinum antitumor agent, JM216, are provided. Such dosage forms provide an alternative to the oral form currently available and offer improved bioavailability of this promising drug.

REFERENCES:
patent: 5049686 (1991-09-01), Hoeschele
patent: 5661142 (1997-08-01), Naeger
Brunner et al. Synthesis and antitumor activity of platinum (II) complexes of benzyl-1,2-diaminoethane ligands. Chem. Ber. 123 (5), 1029-38, 1990.
Lin et al. Grinding effect on some pharmaceutical properties of drugs by adding beta-cyclodextrin. drug. Dev. Ind. Pharm > 14(1), 99-118.
McKeage et al. Cancer. Chemother. Pharmac. vol.36, 451-458, 1995.

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