Jet droplet device

Details Jet droplet device Jet droplet device

1998-05-15

1999-12-14

Ludlow, Jan

Chemical apparatus and process disinfecting, deodorizing, preser

Control element responsive to a sensed operating condition

347 19, 347 85, 422 64, 422 65, 4352864, 4352873, 436518, B01L 302

Patent

active

060013095

ABSTRACT:
Devices and methods are provided for precise reduction of arrays of microspots. A pulse jetting device is employed having a capillary of micron dimensions, with a portion of the capillary proximal to the jetting orifice circumferentially surrounded by a piezoelectric transducer. By appropriate design of the capillary, orifice and piezoelectric transducer, droplets can be formed on a surface, separated by as little as 80 microns center-to-center, and having at least about a 15 micron spacing at the border. The subject substrate arrays can be used for providing miniaturized arrays of reagents, such as nucleic acids, for detecting the presence of homologous sequences in a sample.

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