Istamycins and production thereof

Details Istamycins and production thereof Istamycins and production thereof

1980-04-18

1981-10-20

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

435 80, 536 17R, A61K 3171, C07H 1522

Patent

active

042961068

ABSTRACT:
Four new antibiotics which are denominated istamycin A, istamycin B, istamycin A.sub.o and istamycin B.sub.o, and which are useful as antibacterial agents, are produced by fermentation of a new microorganism, Streptomyces tenjimariensis.

REFERENCES:
patent: 4205070 (1980-05-01), Tadanier et al.
patent: 4216308 (1980-08-01), Iida et al.
Nara, et al., "Jour. Antibiotics", vol. 30, pp. 533-540, 1977.
Okachi, et al., "Jour. Antibiotics", vol. 30, pp. 541-551, 1977.
Egan, et al., "Jour. Antibiotics", vol. 30, pp. 552-563, 1977.
Deushi, et al., "Jour. Antibiotics", vol. 32, pp. 173-179, 187-192 1979.
Iwasaki, et al., "Jour. Antibiotics", vol. 32, pp. 180-186, 1979.
Okami, et al., "Jour. Antibiotics", vol. 32, pp. 964-966, 1979.
Hotta, et al., "Jour. Antibiotics", vol. 33, 1980, pp. 1502-1509, 1510-1514, 1515-1520.

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