ispA from Staphylococcus aureus

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4352523, 4353201, 435325, 536 231, 536 232, 536 234, 536 237, C12P 2106, C12N 120, C12N 1500, C12N 500, C07H 2104

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active

061070580

ABSTRACT:
The invention provides ispA polypeptides and polynucleotides encoding ispA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ispA polypeptides to screen for antibacterial compounds.

REFERENCES:
pBluescript II KS, pp. 38 and 310 of the Stratagene Corporation catalogue, 1997.
Koyama, T., "Micrococcus luteus DNA for farnesyl diphosphate synthase, complete cds", GenBank Submission, Accession No. AB003187, Direct Sumbission, Mar. 25, 1997.
Tomb, et al., "The complete genome sequence of the gastric pathogen Helicobacter pylor", GenBank Submission, Accession No. AE000602, Aug. 6, 1997.
Ogura, K., "B. stearothermophilus DNA for farnesyl diphosphate synthase", GenBank Submission, Accession No. D13293, Direct Submission, Aug. 6, 1993.
Fleischmann, et al., "Whole-genome random sequencing and assembly of Haemophilus influenzae Rd", SwissProt Submission, Accession No. AAC23087, Direct Submission, Sep. 9, 1998.
Fleischmann, et al., "Whole-genome random sequencing and assembly of Haemophilus influenzae Rd", SwissProt Submission, Accession No. C64123PID, May 10, 1996.
Nakane, et al., "Crystallization and Preliminary X-ray Diffraction Studies of Bacillus stearothermophilus farnesyl Disphosphate Synthase Expressed in Escherichia coli", J. Mol. Biol, vol. 233, pp. 787-788, (1993).
Koyama, et al., "Identification of Significant Residues in the Substrate Binding Site of Bacillus stearothermophilus Farnesyl Diphosphate Synthase", Biochemistry, vol. 35, pp. 9533-9538, (1996).
Fujisaki, et al., "Coning and Nucleotide Sequence of the ispA Gene Responsible for Farnesyl Diphosphate Synthase Activity in Escherichia coli", J. Biochem., vol. 108, pp. 995-1000, (1990).
Tarshis, et al., "Crystal Structure of Recombinant Farnesyl Diphosphate Synthase at 2.6-.ANG. Resolution", Biochemistry, vol. 33, pp. 10871-10877, (1994).
Siomoin, et al., "Identification and characterization of ispA, a Shigella flexneri chromosomal gene essential for normal in vivo cell division and intercellular spreading", Molecular Microbiology, vol. 19, No. 3, pp. 599-609, (1996).

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