Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1997-10-17
2000-12-26
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530328, 435 6, 435 78, 435 15, 436 86, A61K 3800
Patent
active
061659770
ABSTRACT:
Isozyme-specific agonists or activators of .epsilon.PKC are disclosed. The agonists include peptides corresponding to the region of .epsilon.PKC between about amino acids 85 and 92. Also disclosed are therapeutic methods employing such .epsilon.PKC-specific agonists to induce preconditioning and thereby reduce injury due to subsequent ischemia, as well as methods for screening test compounds for .epsilon.PKC-selective agonist properties.
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Board of Trustees of the Leland Stanford Junior University
Cintins Marianne M.
Delacroix-Muirheid C.
Mohr Judy M.
Stratford Carol A.
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