Isoxazolo[3,4-d]pyrimidines

Details Isoxazolo[3,4-d]pyrimidines Isoxazolo[3,4-d]pyrimidines

1978-09-27

1980-05-13

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

424251, 544303, 544312, A61K 31505, C07D49104

Patent

active

042029759

ABSTRACT:
Isoxazolo[3,4-d]pyrimidines of the formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3, respectively, are hydrogen, lower alkyl, cycloalkyl, or aryl which may be substituted by halogen, are useful as antiinflammatory-analgesic drugs, and the industrially feasible production thereof is provided.

REFERENCES:
patent: 3056781 (1962-10-01), Papesch
patent: 3517008 (1970-06-01), Kim et al.
patent: 3679682 (1972-07-01), Gibbons
patent: 3803148 (1974-04-01), Gibbons
patent: 3816421 (1974-06-01), Gibbons et al.
Senda, et al. "Pharm. Soc. Japan," 1976, pp. 114.
Pfleiderer, et al., "Annalen der Chemie," vol. 615, 1958, pp. 52-57.
Papesch, et al., "J. Org. Chem.," vol. 30, 1965, pp. 199-203.
Justoni, et al. "Chemical Abstracts," vol. 50, 1956, col. 4127d.

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