Isoxazoline derivatives useful as antimicrobials

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514378, 5462721, 548240, C07D41300, C07D26102, A61K 3144, A61K 3142

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active

059901365

ABSTRACT:
The present invention provides compounds of formula 1 ##STR1## or pharmaceutical acceptable salts thereof wherein A and R.sub.1 are as defined in the claims which are antibacterial agents.

REFERENCES:
patent: 3769295 (1973-10-01), Hoyle et al.
patent: 4283403 (1981-08-01), Davenport
S. S. Ghabrial, et al., Acta Chemica Scandinavica, B 41, pp. 426-434 (1987).
Ghabrial et al. (Acta Chem. Scand., Ser. B (1987), B41(6), 426-34).
Castelhano et al. (Bioorg. Chem. (1988), 16(3), 335-40).

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