Isoxazole substituted nitroimidazoles

Details Isoxazole substituted nitroimidazoles Isoxazole substituted nitroimidazoles

1975-07-30

1977-03-01

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424272, C07D41304

Patent

active

040101762

ABSTRACT:
Novel substituted nitroimidazoles are provided, for example, 2-(4,5-substituted-isoxazol-3-yl)-1-substituted-5-nitroimidazole; 2-(4,5-disubstituted-.DELTA..sup.2 -isoxazolin-3-yl)-1-substituted-5-nitroimidazole; or 2-(4,5-disubstituted-2-loweralkyl-isoxazolidin-3-yl)-1-substituted-5-nitro imidazole. These compounds have antibacterial and antiprotozoal activity, especially against human and animal trypanosomiasis and trichomoniasis.

REFERENCES:
patent: 3472857 (1969-10-01), Arya
patent: 3631169 (1971-12-01), Minami et al.
patent: 3711495 (1973-01-01), Kulsa et al.
patent: 3769295 (1973-10-01), Hoyle et al.
patent: 3915978 (1975-10-01), Kulsa et al.

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