Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-06-13
2006-06-13
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S338000, C514S378000, C546S272100, C546S082000, C548S243000, C548S245000, C548S247000
Reexamination Certificate
active
07060710
ABSTRACT:
The present invention provides compounds of formula I:in which:one of X and Y is a nitrogen atom substituted by a group R6′and the other is a carbon atom substituted by an isoxazole group substituted on its carbon atoms by groups R3and R4;one of R6and R6′is hydrogen;either all of W1, W2, W3and W4are carbon or one of W1, W2, W3and W4is nitrogen and the rest are carbon;and R1and R2are, independently, a small group, heteroaromatic ring or a 4–7 membered cyclic amine ring; processes for making them; pharmaceutical composition containing them; their use in therapy, particularly for enhancing cognition in conditions such as Alzheimer's Disease; and methods of treatment using them.
REFERENCES:
patent: 6462036 (2002-10-01), Doyle et al.
Ladduwahetty Tamara
MacLeod Angus Murray
Merchant Kevin John
Sternfeld Francine
Grazier Nyeemah
Merck Sharp & Dohme Ltd.
Saeed Kamal A.
Todaro John C.
Winokur Melvin
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