Isoxazole compositions useful as inhibitors of ERK

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S378000, C514S254100, C514S307000, C514S316000, C548S245000, C548S246000, C548S247000, C544S137000, C544S367000, C546S272100, C546S146000, C546S189000, C546S209000

Reexamination Certificate

active

07354919

ABSTRACT:
Described herein are compounds that are useful as protein kinase inhibitors, especially inhibitors of ERK, having the formula:where A, B, R1, R2, T and Ht are described in the specification. The compounds are useful for treating diseases in mammals that are alleviated by a protein, kinase inhibitor, particularly diseases such as cancer, inflammatory disorders, restenosis, and cardiovascular disease.

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