Isoureas and isothioureas

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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Details

544320, 544321, C07D23947, A61K 31505

Patent

active

044394357

ABSTRACT:
The compounds are isoureas and isothioureas which have an O- or S- alkylpyrimidone substituent and which are histamine H.sub.2 -antagonists and antiinflammatory agents. A specific compound of this invention is 2-[5-(O-isoureido)pentylamino]-5-(6-methyl-3-pyridyl-methyl)-4-pyrimidone.

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patent: 4084001 (1978-04-01), Durant et al.
patent: 4145546 (1979-03-01), Brown et al.
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patent: 4218452 (1980-08-01), Brown et al.
patent: 4234588 (1980-11-01), Brown et al.
patent: 4305945 (1981-12-01), Ganellin

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