Isotope correlation filter for mass spectrometry

Details Isotope correlation filter for mass spectrometry Isotope correlation filter for mass spectrometry

2007-10-02

2007-10-02

Barlow, John (Department: 2863)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Chemical analysis

C702S027000, C702S031000, C250S281000, C250S282000, C250S286000, C250S287000, C250S42300F

Reexamination Certificate

active

11055530

ABSTRACT:
The present invention relates generally to mass spectrometry and the analysis of chemical samples, and more particularly to methods for processing data obtained therefrom. Disclosed is an improved method for filtering low intensity mass spectral data. More specifically, the invention provides a method for use with digitized mass spectra that facilitates the distinction between low level signals and noise using the correlation of signals therein based on their mass differences.

REFERENCES:
patent: 4583183 (1986-04-01), Winiecki et al.
patent: 5367162 (1994-11-01), Holland et al.
patent: 6188064 (2001-02-01), Koster
patent: 6288389 (2001-09-01), Franzen
S. Bialkowski, “Real Time Digital Filters: Finite Impulse-Response Filters,” Analytical Chemistry, 1988, 60:355A.
V. Andreev, “A Universal Denoising and Peak Picking Algorithm for LC-MS Based on Matched Filtration in the Chromatographic Time Domain,” Analytical Chemistry, 2003, 75: 6314.

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