Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-03-18
1999-03-30
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514258, 514301, A61K 3141
Patent
active
058890343
ABSTRACT:
Isothiazolones having the general structure ##STR1## where A is a monocyclic or bicyclic ring which may contain up to 3 heteroatoms selected from O, S, and N; R.sup.1 and R.sup.2 are substituent groups such as alkyl, alkoxy, hydroxy, nitro, cyano, amino, and carboxy; and R.sup.5 is alkyl, cycloalkyl, phenyl, and Het. The isothiazolones are useful as anti-retroviral agents, anti-inflammatory agents, and anti-atherosclerotic agents.
REFERENCES:
patent: 5620997 (1997-04-01), Bolton
Bolton Gary Louis
Domagala John Michael
Elslager Edward Faith
Gogliotti Rocco Dean
Purchase Terri Stoeber
Ashbrook Charles W.
Gerstl Robert
Warner-Lambert & Company
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