Isothermal transcription based assay for the detection and quant

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 6, 435 911, 435 912, 536 243, 536 2431, 536 2433, C12P 1934, C12Q 168, C07H 2104

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061210234

ABSTRACT:
An isothermal transcription based amplification assay for the detection or quantification of chemokine RNA uses primers and probes for sequences within the gene for RANTES, MIP-l.alpha. and MIP-1 .beta.. The quantitative system uses an internal control Q of a mutant version of each gene. Target specific primers and probes are also disclosed.

REFERENCES:
patent: 5130268 (1992-07-01), Malek et al.
patent: 5234809 (1993-08-01), Boom et al.
patent: 5409818 (1995-04-01), Davey et al.
patent: 5554517 (1996-09-01), Davey et al.
patent: 5616688 (1997-04-01), Cerami et al.
patent: 5834255 (1998-11-01), Van Gemen et al.
Schall et al J. Immunology vol. 141 pp. 1018-1025, 1988.
Ausubel et al Current Protocols in Molecular Biology section 4..03-4.5.2, 1988.
Romano et al., "NASBA a Novel Isothermal Detection Technology for Qualitative and Quantitative HIV-1 RNA Measurements", Clinics in Laboratory Medicine, vol. 16, No. 1, Mar. 1, 1996, pp. 89-103.
Natori et al., "Gene Expression of CC Chemokines in experimental cresentic glomerulonephritis (CGN)", Clinical and Experimental Immunology, vol. 109, 1997, pp. 143-148.
Bisset et al., "Change in Circulating levels of the chemokines macrophage inflammatory proteins 1 alpha and II beta, rantes, monocyte chemotactic protein-1 and interleukin-16 following severely immunodeficient HIV-infected individuals with indinavir", AIDS, vol. 11, No. 4, Mar. 1997, pp. 485-491.
Cocchi et al., "Identification of Rantes, MIP-ALPHA, and MIP-1BETA as the Major HIV-Suppressive Factors Produced by CD8+ T Cells", Science, vol. 270, No. 572, Dec. 15, 1995, pp. 1811-1815.
Schmidtmayerova et al., "Human Immunodeficiency virus type 1 infection alters beta peptide expression in human monocytes into brain and lymph nodes" Proc. Natl. Acad. Sci. USA., vol. 93, Jan. 1996, pp. 700-704.
Bluman et al., "Human Natural Killer Cells Produce Abundant Macrophage Inflammatory Protein-1 Aspire in Response to Monocyte-Derived Cytokines", Journal of Clinical Investigation, vol. 97, No. 12, Jun. 15, 1996, pp. 2722-2727.
Pattison et al., "Rantes Chemokine expression in transplant-associated accelerated atherosclerosis", Journal of Heart and Lung Transplantation, vol. 15, No. 12, Dec. 1, 1996, pp. 1194-1199.
Strehlau, et al., "Quantitative Detection of Immune Activation Transcripts as a Diagnostic Tool in Kidney Transplants", Proc. Natl. Acad. Sci. USA, vol. 94, Jan. 1997, pp. 695-700.
J. Strehlau et al., Proc. Natl. Acad. Sci. USA, 94(2)695-700, 1997.
F. Burke et al., Cytokine, 8(7):578-85 (Abstract) 1996.
H. Schmidtmayoerova et al., Proc. Natl. Acad. Sci. USA, 93(2):700-04, 1996.
S. Michelson et al., J. Virol., 71(9):6495-6500 (Abstract) 1997.
Y. Natori et al., Clin Exp Immunol, 109(1):143-148 (Abstract) 1997.
M. Adachi et al., Int Arch Allergy Immunol, 113(1-3):307-311 (Abstract) 1997.
N. Powell et al., Eur Respir J, 9(12):2454-2560 (Abstract) 1996.
M. Srivastava et al., Res Comm Mol Pathol Pharmacol, 93(3):263-287 (Abstract) 1996.
S. Matsukura et al., J Allergy Clin Immunol, 98(6 Pt 1):1080-87 (Abstract) 1996.
N. Berkman et al., Am J Respir Crit Care Med, 154:(6 Pt 1):1804-11 (Abstract) 1996.
W. Halford et al., J Immunol, 157(8):3542-3549 (Abstract) 1996.
H. Yamada et al., Int Arch Allergy Immunol, 111(Supp 1):19-21 (Abstract) 1996.
K. Lim et al., J. Immunol, 156(7):2566-2570 (Abstract) 1996.
Z. Lummus et al., Toxicology, 111(1-3):191-206 (Abstract) 1996.
B. Canque et al., Blood, 87(5):2011-2019, 1996.
H. Nakajima et al., J Immunol, 156(12):4859-66 (Abstract) 1996.
M. Tran et al., Invest Ophthalmol Vis Sci, 37(6):987-996 (Abstract) 1996.
R. Alam et al., Am J. Respir Crit Care Med, 153:1398-404 (Abstract) 1996.
M. Baba et al., Int J Cancer, 66(1):124-129 (Abstract) 1996.
S. Ying et al., Eur J Immunol, 26(1):70-76 (Abstract) 1996.
C. Power et al., Cytokine, 7(6):479-482, 1995.
Y. Su et al., J Virol, 70(2):1277-1281 (Abstract) 1996.
J. Wang et al., Am J Respir Cell Mol Biol, 14(1):27-35 (Abstract) 1996.
C. Gelder et al., Thorax, 50(10):1033-1037 (Abstract) 1995.
L. Zhou et al., Blood, 86(9):3295-3301 (Abstract) 1995.
S. Matsukura et al., Arerugi, 44(7):715-717 (Abstract) 1995.
K. Nadeau et al., Proc Natl Acad Sci USA, 92(19):8729-33 (Abstract) 1995.
C. Melani et al., Int J Cancer, 62(5):572-578 (Abstract) 1995.
R. Godiska et al., J. Neuroimmunol, 58(2):167-176 (Abstract) 1995.
S. Hosaka et al., Clin Exp Immunol, 97(3):451-457 (Abstract) 1994.
I. Beckman et al., Cytokine, 6(2):116-123 (Abstract) 1994.
A. Whyte et al., Lancet, 343(8908):1291-1292 (Abstract) 1994.
P Heeger et al., Kidney Int, 41(1):220-225 (Abstract) 1992.
C. Plater-Zybrek et al., Immunology Letters, 57(1-3):117-120 (Abstract) 1997.
M. Petrek et al., European Respiratory Journal, 10(6):1207-1216 (Abstract) 1997.
J. Kim et al, J of the Korean Soc of Microbio, 30(6):651-653 (Abstract) 1995.
D. Kuhn et al., Biochemical and Biophysical Research Communications, 211(1):325-330, 1995.
D. Gilat et al., The Journal of Immunology, 4899-4906, 1994.
E. Scala et al., The Journal of Immunology, 4485-4492, 1997.
T. Dragic et al., Nature, 381:667-673, 1996.
F. Cocchi et al., Nature Medicine, 2:11:1244-1247, 1996.
B. Premack et al., Nature Medicine, 2:11-1174-1178, 1996.
M. D'Souza et al., Nature Medicine, 2:12-1293-1300, 1996.
W. Paxton et al., Nature Medicine, 2:4:412-417, 1996.

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