Isoquinoline thromboxane synthetase inhibitors

Details Isoquinoline thromboxane synthetase inhibitors Isoquinoline thromboxane synthetase inhibitors

1985-01-22

1986-04-22

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21714

Patent

active

045843791

ABSTRACT:
4-[(4-Isoquinolinylmethyl)amino]benzoic acid derivatives useful as selective thromboxane synthetase inhibitors are described herein. The compounds are obtained from the appropriate 4-isoquinolinecarboxylic acid derivative and an aminobenzoic acid derivative. This gives the corresponding Schiff base which is then reduced to give the desired compounds.

REFERENCES:
patent: 3707470 (1972-12-01), Sawa et al.
patent: 3994907 (1976-11-01), Maeda et al.
patent: 4241068 (1980-12-01), Schromm et al.
patent: 4260611 (1981-04-01), Bartmann et al.
patent: 4373104 (1983-02-01), Takaes et al.
Derwent Abstract: 10254x/06.
Partridge, et al., "J. Chem. Soc.", 1964, pp. 3673-3678.
Djudovic, et al., "Pharmazie.," vol. 31(12), 1976, pp. 845-848.
Mertes, et al., "J. Med. Chem.", vol. 13(2), 1970, pp. 276-279.

Affiliated with

Also associated with

Rating

Isoquinoline thromboxane synthetase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Isoquinoline thromboxane synthetase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isoquinoline thromboxane synthetase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1916280